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Invitrogen™ ELOVL6 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA513455
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Descripción
This antibody is predicted to react with chicken and rat based on sequence homology.
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
Especificaciones
| ELOVL6 | |
| Polyclonal | |
| Unconjugated | |
| ELOVL6 | |
| 3-keto acyl-CoA synthase Elovl6; C77826; Elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL family member 6, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 6; ELOVL6; FACE; FAE; fatty acid elongase 2; Fatty acyl-CoA elongase; hELO2; Lce; Lce2; long chain fatty acid elongase; long chain fatty acyl elongase; long-chain fatty-acyl elongase; Masr; Myelin-associated SUR4 protein; rELO2; Very long chain 3-ketoacyl-CoA synthase 6; very long chain 3-oxoacyl-CoA synthase 6; very-long-chain 3-oxoacyl-CoA synthase 6 | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 170439, 79071 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
| 2 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| Q920L5, Q9H5J4 | |
| ELOVL6 | |
| KLH conjugated synthetic peptide between 32-58 amino acids from the N-terminal region of human ELOVL6. | |
| 400 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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