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Invitrogen™ ELOVL6 Polyclonal Antibody
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Código de producto. 10813461
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Cantidad:
400 μL
Tamaño de la unidad:
100 microgramos
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10813461 400 μL 100 microgramos
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Código de producto. 10813461 Proveedor Invitrogen™ N.º de proveedor PA513455

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Descripción

Rabbit Polyclonal Antibody

This antibody is predicted to react with chicken and rat based on sequence homology.

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
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Especificaciones

Antígeno ELOVL6
Aplicaciones Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 2 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.09% sodium azide; pH 7.4
génica ELOVL6
N.º de referencia del gen Q920L5, Q9H5J4
Alias de gen 3-keto acyl-CoA synthase Elovl6; C77826; Elongation of very long chain fatty acids protein 6; ELOVL FA elongase 6; ELOVL family member 6, elongation of long chain fatty acids; ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL family member 6, elongation of long chain fatty acids (yeast); ELOVL fatty acid elongase 6; ELOVL6; FACE; FAE; fatty acid elongase 2; Fatty acyl-CoA elongase; hELO2; Lce; Lce2; long chain fatty acid elongase; long chain fatty acyl elongase; long-chain fatty-acyl elongase; Masr; Myelin-associated SUR4 protein; rELO2; Very long chain 3-ketoacyl-CoA synthase 6; very long chain 3-oxoacyl-CoA synthase 6; very-long-chain 3-oxoacyl-CoA synthase 6
Símbolos de los genes ELOVL6
Especie del huésped Rabbit
Inmunógeno KLH conjugated synthetic peptide between 32-58 amino acids from the N-terminal region of human ELOVL6.
Método de purificación Ammonium sulfate precipitation, Size-exclusion - Dialysis
Cantidad 400 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 170439, 79071
Especies diana Human, Mouse
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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