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Invitrogen™ DARC Polyclonal Antibody
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Código de producto. 17297853 Tienda Thermo Scientific Productos
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
17297853 100 μL 100 microlitros
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Código de producto. 17297853

Marca: Invitrogen™ PA5115094

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Descripción

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total DARC.

ACKR1 or DARC is an atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades resulting instead in chemokine sequestration, degradation, or transcytosis. ACKR1 is also known as an interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. It has a promiscuous chemokine-binding profile by interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. ACKR1 also acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and for the malaria parasites P.vivax and P.knowlesi.
TRUSTED_SUSTAINABILITY

Specifica

Antígeno DARC
Aplicaciones Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.02% sodium azide
génica ACKR1
N.º de referencia del gen Q16570, Q9QUI6
Alias de gen AA162249; ACKR1; Atypical chemokine receptor 1; atypical chemokine receptor 1 (Duffy blood group); CCBP1; CD234; CD234 antigen; CTA-134P22.3; DARC; Dfy; Duffy Antigen; Duffy antigen chemokine receptor; Duffy antigen receptor for chemokines; duffy antigen/chemokine receptor; Duffy blood group antigen; duffy blood group chemokine receptor; Duffy blood group, atypical chemokine receptor; Duffy blood group, chemokine receptor; ESTM35; FY; Fy Antigen; Fy glycoprotein; FYDuffy blood group; glycoprotein D; GPD; GPDWBCQ1; GpFy; HGNC:4035; OTTHUMP00000060081; Plasmodium vivax receptor; WBCQ1
Símbolos de los genes ACKR1
Especie del huésped Rabbit
Inmunógeno A synthesized peptide derived from human ACKR1(Accession Q16570), corresponding to amino acid residues M1-P37.
Método de purificación Affinity Chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 13349, 2532, 689105
Especies diana Human, Mouse, Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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