missing translation for 'onlineSavingsMsg'
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Descripción
Immunogen sequence: KSKTLDFIDV LLLSKDEDGK ALSDEDI Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
CYP4F isoforms are involved in the oxidation of important cellular mediators, such as leukotriene B4 (LTB4) and prostaglandins. CYP4F2 catalyzes omega-hydroxylation of LTB4 to a less potent proinflammatory eicosanoid, 20-OH-LTB4 as well as arachidonic acid. CYP4F2 is expressed in liver and kidney. Its expression is repressed by peroxisomal proliferators and induced by retinoic acid. X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder biochemically characterized by elevated levels of very long-chain fatty acids (VLCFA). CYP4F2 participates in the omega-hydroxylation of VLCFAs, which may provide an alternative mode of treatment for X-ALD patients.
Especificaciones
Especificaciones
| Antígeno | CYP4F2 |
| Aplicaciones | Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.05 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | CYP4F2 |
| N.º de referencia del gen | P78329 |
| Alias de gen | 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; Arachidonic acid omega-hydroxylase; CPF2; CYP4F2; CYPIVF2; cytochrome P450 4F2; cytochrome P450 family 4 subfamily F member 2; cytochrome P450, family 4, subfamily F, polypeptide 2; cytochrome P450, subfamily IVF, polypeptide 2; cytochrome P450-LTB-omega; Docosahexaenoic acid omega-hydroxylase; docosahexaenoic acid omega-hydroxylase CYP4F3; phylloquinone omega-hydroxylase CYP4F2; leukotriene-B(4) 20-monooxygenase 1; Leukotriene-B(4) omega-hydroxylase 1; phylloquinone omega-hydroxylase CYP4F2 |
| Símbolos de los genes | CYP4F2 |
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Título del producto
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