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Invitrogen™ CYP3A4/CYP3A5 Monoclonal Antibody (F24 P2 B10)
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Código de producto. 11595742
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
11595742 100 μL 100 microlitros
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Código de producto. 11595742

Marca: Invitrogen™ MA3032

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Descripción

Mouse Monoclonal Antibody

MA3-032 detects Cytochrome P450 3A4/3A5 from human cell line HepG2, and from bovine liver and pancreas samples. MA3-032 has been successfully used in Western blot applications. By Western blot, this antibody detects a ~54 kDa band representing Cytochrome P450 3A4/3A5. The MA3-032 immunogen is a synthetic peptide corresponding to residues E S R D G T V S G A, conjugated to ovalbumin.

CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CYP3A4/CYP3A5
Aplicaciones Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon F24 P2 B10
Concentración Conc. Not Determined
Conjugado Unconjugated
Formulación Ascites with 0.05% sodium azide
génica CYP3A4
N.º de referencia del gen P08684, P20815
Alias de gen 1,8-cineole 2-exo-monooxygenase; albendazole monooxygenase; Albendazole monooxygenase (sulfoxide-forming); Albendazole sulfoxidase; aryl hydrocarbon hydroxylase; cholesterol 25-hydroxylase; CP33; CP34; CP35; CYP3A; CYP3A28; CYP3A3; CYP3A4; CYP3A5; CYPIIIA28; CYPIIIA3; CYPIIIA4; CYPIIIA5; cytochrome P450; cytochrome P450 3A28; cytochrome P450 3A3; Cytochrome P450 3A4; cytochrome P450 3A5; cytochrome P450 family 3 subfamily A member 4; cytochrome P450 family 3 subfamily A member 5; cytochrome P450 HLp; cytochrome P450 HLp2; cytochrome P450 NF-25; cytochrome P450, family 3, subfamily A, polypeptide 4; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450, subfamily IIIA, polypeptide 4; cytochrome P450-PCN1; Cytochrome P450-PCN3; flavoprotein-linked monooxygenase; glucocorticoid-inducible P450; HLP; HLp2; microsomal monooxygenase; NF-25; Nifedipine oxidase; P450C3; P450-III, steroid inducible; P450PCN1; P450PCN3; P450-PCN3; PCN3; Quinine 3-monooxygenase; taurochenodeoxycholate 6-alpha-hydroxylase; Unknown (protein for MGC:127840); xenobiotic monooxygenase
Símbolos de los genes CYP3A4, CYP3A5
Especie del huésped Mouse
Inmunógeno Synthetic peptide corresponding to residues E S R D G T V S G A, conjugated to ovalbumin.
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 1576, 1577, 282214, 507988, 526682
Especies diana Bovine, Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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