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Invitrogen™ CYP2R1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5111167
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Descripción
Immunogen sequence: TYEDTDFQHM IELFSENVEL AASASVFLYN AFPWIGILPF GKHQQLFRNA AVVYDFLSRL IEKASVNRKP QLPQHFVDAY LDEMDQGKND PSSTFSKENL IFSVGELIIA GTETTTNVLR Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 92%.
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
Especificaciones
| CYP2R1 | |
| Polyclonal | |
| Unconjugated | |
| Cyp2r1 | |
| Cyp2r1; Cytochrome P450 2R1; cytochrome P450 family 2 subfamily R member 1; cytochrome P450, 2r1; cytochrome P450, family 2, R1; cytochrome P450, family 2, subfamily R, polypeptide 1; vitamin D 25-hydroxylase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 120227 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.6 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q6VVX0 | |
| Cyp2r1 | |
| Recombinant Protein corresonding to Human CYP2R1. Recombinant protein control fragment (Product #RP-90562). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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