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Invitrogen™ CYP2C19 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA525906
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Descripción
CYP2C19 Polyclonal Antibody for Western Blot, IHC (P), ICC/IF
CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within its gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes.
Especificaciones
| CYP2C19 | |
| Polyclonal | |
| Unconjugated | |
| CYP2C19 | |
| (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CPCJ; CYP2C; CYP2C19; CYPIIC17; CYPIIC19; cyto; cytochrome P450 2C19; cytochrome P450 family 2 subfamily C member 19; cytochrome P-450 II C; cytochrome P450, family 2, subfamily C, polypeptide 19; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; cytochrome P450-11A; Cytochrome P450-254C; Fenbendazole monooxygenase (4'-hydroxylating); flavoprotein-linked monooxygenase; mephenytoin 4'-hydroxylase; mephenytoin 4-hydroxylase; microsomal monooxygenase; P450-11A; P450-254C; P450C2C; P450IIC19; S-mephenytoin 4-hydroxylase; xenobiotic monooxygenase | |
| Rabbit | |
| Size-exclusion - Dialysis, Ammonium sulfate precipitation | |
| RUO | |
| 1557 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 2.0 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| P33261 | |
| CYP2C19 | |
| KLH conjugated synthetic peptide between 82-108 amino acids from the N-terminal region of human CYP2C19. | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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