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Invitrogen™ Cyclin C Polyclonal Antibody

Descripción
Immunogen sequence: GNFWQSSHYL QWILDKQDLL KERQKDLKFL SEEEYWKLQI FFTNVIQALG E Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.
Especificaciones
Especificaciones
| Antígeno | Cyclin C |
| Aplicaciones | Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.05 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | CCNC |
| N.º de referencia del gen | P24863 |
| Alias de gen | AI451004; AU020987; CCNC; CG1C; CycC; cyclin C; cyclin-C; dJ199J3.4 (cyclin C); hSRB11; SRB11 homolog |
| Símbolos de los genes | CCNC |
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Título del producto
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