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Invitrogen™ CRALBP Recombinant Rabbit Monoclonal Antibody (JE35-09)

Descripción
Positive control: Rat eyeball tissue lysate, mouse eyeball tissue lysate, B16F1. Predicted band size: 36.5 kDa Subcellular Location: Cytoplasm.
Cellular retinaldehyde-binding protein (CRALBP) plays an important role in the regeneration of 11-cis-retinal for use in rod visual pigments such as opsin and rhodopsin. Once 11-cis-retinal is photoisomerized in the rod outer segment, it is converted to all-trans-retinal and further modified into all-trans-retinol. All-trans-retinol then diffuses into the retinal pigment epithelium (RPE) to be converted back to 11-cis-retinol and further oxidized into 11-cis-retinal (both by CRALBP). Genetic mutations involving CRALBP's lack of function have been linked to visual disease such as bothnia dystrophy, retinitis punctata albescens, retina pigmentosa, and Newfoundland rod-cone dystrophy. The presence of CRALBP serves as a marker for RPE and Muller glial cells of the retina.
Especificaciones
Especificaciones
| Antígeno | CRALBP |
| Aplicaciones | Flow Cytometry, Western Blot, Immunocytochemistry |
| Clasificación | Recombinant Monoclonal |
| Clon | JE35-09 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 |
| génica | RLBP1 |
| N.º de referencia del gen | Q9Z275 |
| Alias de gen | 3110056M11Rik; cellular retinaldehyde-binding protein; cellular retinaldehyde-binding protein-1; CRALBP; retinaldehyde binding protein 1; retinaldehyde-binding protein 1; retinaldehyde-binding protein precursor; Rlbp1 |
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Nom du produit
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