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Invitrogen™ CLEC5A Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA534928
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Descripción
Recommended positive controls: K562. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
Especificaciones
| CLEC5A | |
| Polyclonal | |
| Unconjugated | |
| CLEC5A | |
| CLEC5A; Clecsf5; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin domain family 5, member a; C-type lectin superfamily member 5; Ly100; Mdl1; MDL-1; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; type II transmembrane protein MDL-1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 23601, 23845 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q9NY25, Q9R007 | |
| CLEC5A | |
| Recombinant protein encompassing a sequence within the Extracellular domain of human CLEC5A. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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