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Description
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.
Specifications
Specifications
| Antígeno | CHI3L1 |
| Aplicaciones | Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.17 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | CHI3L1 |
| N.º de referencia del gen | P36222, Q61362, Q9WTV1 |
| Alias de gen | 39 kDa synovial protein, ASRT7, Cartilage glycoprotein 39, CGP 39, CHI3L1, Chitinase 3 like protein 1, GP 39, GP39, HC gp39, hCGP 39, HCGP 3P, YKL 40, YKL40, YYL 40 |
| Símbolos de los genes | Chi3l1 |
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