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CENPO Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 20611-1-AP-20UL
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Descripción
Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.Especificaciones
| CENPO | |
| Polyclonal | |
| Unconjugated | |
| CENPO | |
| CENP O, CENPO, centromere protein O, ICEN36, MCM21R | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 52504, 684439, 79172 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.35 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8K015, Q9BU64 | |
| Cenpo | |
| CENPO Fusion Protein Ag14619 | |
| 20 μL | |
| Primary | |
| Mouse, Human, Rat | |
| Antibody | |
| IgG |
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