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Thermo Scientific™ CellSensor™ NFKB-bla Freestyle™ HEK293F Cell Line

Product Code. 10194603
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Cantidad:
1 vial
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cada uno
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Product Code. 10194603

missing translation for 'mfr': Thermo Scientific™ K1663

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Description

Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease.

Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease. The CellSensor™ NFκB-bla FreeStyle™ 293F Cell Line is responsive to tumor necrosis factor alpha (TNFα) and can be used to probe the NFκB signaling pathway. This cell line was validated for DMSO tolerance, incubation time with stimulant and substrate loading conditions. The CellSensor™ NFκB-bla FreeStyle™ 293F Cell Line contains a beta-lactamase reporter gene under the control of NFκB response element. The construct was transduced into FreeStyle™ 293F cells by lentivirus. This cell line is a pool isolated for response to TNFα by flow cytometry. It responds to agonist treatment as expected from literature. Academic and non-profit customers, please inquire for special pricing.

TRUSTED_SUSTAINABILITY

Specifications

Entrada del ensayo Gen informador de beta lactamasa a base de células
Estado de célula Células divisoras
Contenido y almacenamiento Las líneas de células CellSensor™ se envían en hielo seco. Se debe almacenar en nitrógeno líquido inmediatamente después de su recepción, o descongelar para su uso inmediato.
Para utilizar con (aplicación) Citocinas, vía de señalización
Línea de productos CellSensor
Cantidad 1 vial
Entrada diana TNF alfa, NIK, TLR, I kappa B, IRAK, IKK, ruta NF-kappa B
Tipo Células en proceso de división
System Type CellSensor™
Druggable Target Ruta de señalización

Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.

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