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  6. CD54 (ICAM-1) Rat, anti-Mouse, Unconjugated, Clone: YN1/1.7.4, STEMCELL Technologies

CD54 (ICAM-1) Rat, anti-Mouse, Unconjugated, Clone: YN1/1.7.4, STEMCELL Technologies

Código de producto. 17139191
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Cantidad:
50 μg
500 μg
Tamaño de la unidad:
50 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17139191 50 μg 50 microgramos
17129191 500 μg 500 microgramos
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Código de producto. 17139191

Marca: Stemcell Technologies 60151.1

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Description

Rat Monoclonal Antibody

  • The YN1/1.7.4 antibody reacts with CD54, a 90 - 110 kDa type I transmembrane glycoprotein that is a member of the immunoglobulin (Ig) superfamily
  • CD54 consists of five Ig-like C2 type domains and has two isoforms generated from alternative splicing
  • As an important intercellular adhesion molecule, CD54 is involved in inflammatory reactions, antigen-specific immune responses, lymphocyte trafficking, and T cell signal transduction events
  • CD54 mediates important cell-cell interactions and adhesion reactions by binding to its major ligands, LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18)
  • CD54 may also act as a receptor for rhinoviruses and some coxsackieviruses
  • CD54 is expressed on lymphocytes, monocytes, macrophages, dendritic cells, endothelial cells, and high endothelial venules
  • Expression of CD54 is upregulated on activated lymphocytes and also, following stimulation with inflammatory mediators such as cytokines, LPS, and IFN-γ

Specifications

Antígeno CD54 (ICAM-1)
Aplicaciones Immunoblot, Flow Cytometry, Immunoprecipitation
Clasificación Monoclonal
Clon YN1/1.7.4
Conjugado Unconjugated
Especie del huésped Rat
Cantidad 50 μg
Primario o secundario Primary
Especies diana Mouse
Isotype IgG2b κ
Tipo de célula Endothelial Cells
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