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CD51 (Integrin αV) Mouse, anti-Human, PE, Clone: NKI-M9, STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 60043PE
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Descripción
- The NKI-M9 antibody reacts with CD51 (vitronectin receptor α chain, or integrin αV), a type I transmembrane glycoprotein containing two subunits (125 kDa and 24 kDa) which are generated by post-translational cleavage and are linked by a disulfide bond
- CD51 associates non-covalently with integrin β1 (CD29), β3 (CD61), β5, β6, or β8 to form heterodimeric cell adhesion receptors for extracellular matrix components such as fibrinogen, collagen, fibronectin, laminin, osteopontin, thrombospondin, vitronectin, and von Willebrand factor
- For example, association of CD51 and CD61 forms the integrin αv/β3 receptor primarily involved in binding vitronectin
- CD51 is expressed broadly on many types of cells, including endothelial cells, fibroblasts, monocytes, macrophages, platelets (at relatively low levels), and osteoclasts
- It is also found on hepatoma, melanoma, and neuroblastoma cells
Especificaciones
| CD51 (Integrin αV) | |
| Monoclonal | |
| PE | |
| 100 Tests | |
| Human | |
| Mesenchymal Stem and Progenitor Cells |
| Immunoprecipitation, ELISA, Flow Cytometry, Functional Assay | |
| NKI-M9 | |
| Mouse | |
| Primary | |
| IgG2a κ |
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Título del producto
CD51 (Integrin αV) Mouse, anti-Human, PE, Clone: NKI-M9, STEMCELL Technologies
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