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CD4 Mouse, anti-Human, Biotin, Clone: OKT4, STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 60016BT
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Descripción
- The OKT4 antibody reacts with CD4, an ∼59 kDa single-chain type 1 transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily; CD4 contains four extracellular Ig-like domains (D1 - D4)
- The epitope for OKT4 has been localized to the D3 domain of the protein, which has a structure resembling an Ig variable domain
- CD4 is expressed at high levels by most thymocytes and a subpopulation of T cells (T-helper cells), and at lower levels by peripheral blood monocytes and macrophages
- Moreover, CD4 is a receptor for human immunodeficiency virus (HIV)
- Binding of the OKT4 antibody to CD4 does not block HIV binding
- This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Direct Human CD4+ T Cell Isolation Kit (Catalog #19662), EasySep™ Human CD4+ T Cell Enrichment Kit (Catalog #19052), EasySep™ Human CD3 Positive Selection Kit II (Catalog #17851) and EasySep™ Human CD4 Positive Selection Kit II (Catalog #17852)
Especificaciones
| CD4 | |
| Monoclonal | |
| Biotin | |
| 100 μg | |
| Cynomolgus, Rhesus Monkey, Sooty Mangabey, Chimpanzee, Human | |
| T Cells, T Cells, CD4+, T Cells, Regulatory |
| Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Immunoprecipitation | |
| OKT4 | |
| Mouse | |
| Primary | |
| IgG2b κ |
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