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Invitrogen™ CD304 (Neuropilin-1) Recombinant Rabbit Monoclonal Antibody (ST05-30)
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Código de producto. 16315604
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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16315604 100 μL 100 microlitros
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Código de producto. 16315604 Proveedor Invitrogen™ N.º de proveedor MA532179

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Descripción

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain. Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors. Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system. This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis. Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.
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Especificaciones

Antígeno CD304 (Neuropilin-1)
Aplicaciones Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunohistochemistry, Western Blot
Clasificación Recombinant Monoclonal
Clon ST05-30
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
génica NRP1
N.º de referencia del gen O14786, P97333, Q9QWJ9
Alias de gen A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R
Símbolos de los genes NRP1
Especie del huésped Rabbit
Inmunógeno Synthetic peptide within Human Neuropilin-1 aa 881-923.
Método de purificación Protein A
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 18186, 246331, 8829
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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