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CD3 Mouse anti-Human, APC, Clone: UCHT1, BD
Description
The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.
Specifications
Specifications
| Antígeno | CD3 |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Clon | UCHT1 |
| Conjugado | APC |
| Formulación | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Especie del huésped | Mouse |
| Inmunógeno | Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor |
| Método de purificación | Affinity Purified |
| Cantidad | 25 Tests |
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For Research Use Only.
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