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Invitrogen™ CD275 (B7-H2) Polyclonal Antibody
Goat Polyclonal Antibody
Marca: Invitrogen™ PA547177
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Description
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse B7-H2 and recombinant human B7-H1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
Specifications
| CD275 (B7-H2) | |
| Polyclonal | |
| Unconjugated | |
| ICOSLG | |
| AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand | |
| Goat | |
| Antigen Affinity Chromatography | |
| RUO | |
| 23308 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| O75144 | |
| ICOSLG | |
| Mouse myeloma cell line NS0-derived recombinant human B7-H2 Asp19-Ser258. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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