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CD263 (TRAIL-R3) Polyclonal Antibody, Invitrogen™

Código de producto. 11518661
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
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11518661 100 μg 100 microgramos
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Product Code. 11518661 Supplier Invitrogen Supplier No. PA1956

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Description

Rabbit Polyclonal Antibody

PA1-956 detects decoy receptor 1 (DcR1) from human and rat tissues and cells. PA1-956 has been successfully used in FACS and Western blot procedures. By Western blot, this antibody detects an ∽30 kDa protein representing DcR1 from HEK293 cell lysate. PA1-956 immunizing peptide corresponds to amino acid residues 24-35 of human DcR1. PA1-956 immunizing peptide (Cat. No. PEP-047) is available for use in neutralization and control experiments.

DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno CD263 (TRAIL-R3)
Aplicaciones Flow Cytometry, Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
génica TNFSF10
N.º de referencia del gen O14798, P50591
Alias de gen CD263, DCR1, LIT, MGC149501, MGC149502, TRAILR3, TRID
Símbolos de los genes TNFRSF10C, TNFSF10
Especie del huésped Rabbit
Inmunógeno Synthetic Peptide: Y(24) S A T T A R Q E E V P(35) C
Método de purificación Antigen affinity chromatography
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 246775, 8743, 8794
Especies diana Human, Rat
Contenido y almacenamiento -20° C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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