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CD235ab (Glycophorin A/B) Mouse, anti-Human, Unconjugated, Clone: HIR2 (GA-R2), STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 60111
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Descripción
- The HIR2 (GA-R2) antibody recognizes an epitope common to the N-terminal region of human CD235a (glycophorin A) and CD235b (glycophorin B), homologous type I sialoglycoproteins of the erythrocyte (red blood cell) membrane that bear the antigenic determinants for the MN and Ss blood groups
- CD235ab is expressed on early- and late-stage erythroblasts, mature erythrocytes, and erythroid cell lines such as K562 and HEL, but not on other cell types
- CD235a is abundantly expressed whereas CD235b is a relatively minor membrane component
- The proteins are believed to provide a large mucin-like surface to erythrocytes that acts to minimize aggregation in the circulation
- The HIR2 antibody binds with higher affinity to CD235a than CD235b, and agglutinates untreated erythrocytes
Especificaciones
| CD235ab (Glycophorin A/B) | |
| Monoclonal | |
| Unconjugated | |
| 100 μg | |
| Human | |
| Red Blood Cells |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| HIR2 (GA-R2) | |
| Mouse | |
| Primary | |
| IgG2b κ |
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Título del producto
CD235ab (Glycophorin A/B) Mouse, anti-Human, Unconjugated, Clone: HIR2 (GA-R2), STEMCELL Technologies
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