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CD229 Monoclonal Antibody (HLy 9.1.25), PE, Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA135946
Detalles adicionales : Peso : 0.01000kg
Descripción
The reagent is designed for analysis of human blood cells using 10 μL reagent/ 100 μL of whole blood or 10^6 cells in a suspension.
CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.Especificaciones
CD229 | |
Monoclonal | |
PE | |
Ly9 | |
AI893573; CD229; CDABP0070; Cell surface molecule Ly-9; hly9; Lgp100; LY9; Ly-9; Lymphocyte antigen 9; mLY9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T100; T-lymphocyte surface antigen Ly-9 | |
Mouse | |
purified | |
RUO | |
4063 | |
4° C, store in dark | |
Liquid |
Flow Cytometry | |
HLy 9.1.25 | |
PBS with 1% BSA and 0.09% sodium azide | |
Q9HBG7 | |
Ly9 | |
Mouse pre-B cell line 300.19 transfected with CD229 cDNA. | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG1 |