missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ CD223 (LAG-3) Monoclonal Antibody (3DS223H), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™
Descripción
LAG-3 is a 70-kDa surface glycoprotein in the immunoglobulin superfamily, with structural homology to CD4. It binds to MHC class II molecules with higher affinity than CD4 and is involved in the negative regulation of T cell activation and homeostatic proliferation. LAG-3 is expressed on the surface of activated T cells, including regulatory T cells, and NK cells. Notably, CD8+ T cells express LAG-3 at significantly higher levels than CD4+ T cells. Additionally, the coexpression of LAG-3 and CD49b has been proposed as a marker for identifying Type 1 regulatory T cells (Tr1 cells) in both humans and mice. This highlights LAG-3s role in immune regulation and its potential as a target for therapeutic interventions in immune-related conditions.
Especificaciones
Especificaciones
| Antígeno | CD223 (LAG-3) |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Clon | 3DS223H |
| Concentración | 0.4 μg/Test |
| Conjugado | NovaFluor Yellow 610 |
| Formulación | PBS with 0.09% sodium azide; pH 7.2 |
| génica | LAG3 |
| N.º de referencia del gen | P18627 |
| Alias de gen | Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3 |
| Mostrar más |
Título del producto
Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.
¿Detecta una oportunidad de mejora?