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CD223 (LAG-3) Monoclonal Antibody (3DS223H), NovaFluor™ Yellow 590, eBioscience™, Invitrogen™
Descripción
LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Especificaciones
Especificaciones
| Antígeno | CD223 (LAG-3) |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Clon | 3DS223H |
| Concentración | 0.4 μg/Test |
| Conjugado | NovaFluor Yellow 590 |
| Formulación | PBS with 0.09% sodium azide; pH 7.2 |
| génica | LAG3 |
| N.º de referencia del gen | P18627 |
| Alias de gen | Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3 |
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Título del producto
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