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CD206 Mouse anti-Human, FITC, Clone: 15-2, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech FITC-65155-100TESTS
Detalles adicionales : Peso : 0.00010kg
Descripción
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.
Especificaciones
CD206 | |
Monoclonal | |
4 μL/Test | |
Mouse | |
Primary | |
Human, Mouse | |
IgG1 κ |
Flow Cytometry | |
15-2 | |
FITC | |
100 Tests | |
4360 | |
Liquid |