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CD200 Monoclonal Antibody (OX90), Biotin, Invitrogen™
Rat Monoclonal Antibody
Marca: Invitrogen MA517979
Detalles adicionales : Peso : 0.01000kg
Descripción
MA5-17979 targets CD200/OX-2 in ELISA, FACS, and IHC applications and shows reactivity with Mouse samples. The MA5-17979 immunogen is mouse CD200-rat CD4 fusion protein.
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.Specifications
| CD200 | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
| O54901 | |
| Cd200 | |
| mouse CD200-rat CD4 fusion protein | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| ELISA, Flow Cytometry, Immunohistochemistry | |
| OX90 | |
| Biotin | |
| Cd200 | |
| antigen identified by monoclonal antibody MRC OX-2; CD200; Cd200 antigen; Cd200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2); Cspmo2; hypothetical protein LOC534910; MOX1; MOX2; MRC; MRC OX-2 antigen; MRCOX2; My033; OX2; OX-2; OX-2 membrane glycoprotein | |
| Rat | |
| Protein G | |
| RUO | |
| 17470 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |