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CD1d Mouse anti-Human, Brilliant Violet 650, Clone: CD1d42 (also known as 42.1), BD Optibuild™

Código de producto. 15898379
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Cantidad:
50 μg
Tamaño de la unidad:
cada uno
Código de producto. Cantidad unitSize
15898379 50 μg cada uno
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Product Code. 15898379

Brand: BD Biosciences 743606

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Description

Mouse Monoclonal Antibody

The CD1d42 monoclonal antibody recognizes CD1d. Cell surface CD1d is structurally homologous to Class I MHC molecules. It consists ofa glycosylated type I transmembrane α chain (43-49 kDa) that is non-covalently associated with β2-microglobulin. CD1d is a member of the CD1 family of molecules, which belong to the immunoglobulin superfamily. Sequence homology data classifies the CD1 molecules into two groups. Group 1 includes CD1a, CD1b andCD1c molecules; group 2 includes CD1d molecules and their homologs in other species. CD1d is expressed on cortical thymocytes, B cells, dendritic cells, monocytes, and some nonlymphoid cells including intestinal epithelial cells, hepatocytes and keratinocytes. It is not expressed on resting mature T cells. Studies suggest that CD1d participates in lipid antigen presentation to CD1d-restricted NKT cells

The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 650nm. BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination. BV650 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 650 nm. Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. BV650 will have moderate spillover into the BD Horizon™ BV711 detector.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno CD1d
Clasificación Monoclonal
Clon CD1d42 (also known as 42.1)
Concentración 0.2mg/mL
Conjugado Brilliant Violet 650
Formulación Aqueous buffered solution containing ≤0.09% sodium azide.
Alias de gen R3, R3G1, HMC class I antigen-like glycoprotein CD1D
Especie del huésped Mouse
Inmunógeno Human CD1d Recombinant Protein
Método de purificación Affinity Purified
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
Especies diana Human
Contenido y almacenamiento Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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