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CD171 Monoclonal Antibody (UJ127), Biotin, Invitrogen™
Descripción
MA5-14137 targets L1 Cell Adhesion Molecule in IHC (P), IP, and WB applications and shows reactivity with Human samples. The MA5-14137 immunogen is homogenous suspension of 16 week human fetal brain.
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Especificaciones
Especificaciones
| Antígeno | CD171 |
| Aplicaciones | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Clasificación | Monoclonal |
| Clon | UJ127 |
| Concentración | 0.2 mg/mL |
| Conjugado | Biotin |
| Formulación | PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 |
| génica | L1CAM |
| N.º de referencia del gen | P32004 |
| Alias de gen | antigen identified by monoclonal antibody R1; CAML1; CD 171; CD171; CD171 molecule; HSAS; HSAS1; Hyd; L1; L1 cell adhesion molecule; L1CAM; MASA; MIC5; N-CAM L1; NCAML1; N-CAML1; N-CAM-L1; NCAM-L1; Nerve-growth factor-inducible large external glycoprotein; neural cell adhesion molecule L1; NILE; S10; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM; SPG1 |
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Título del producto
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