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Invitrogen™ CD148 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5119082
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Descripción
CD148 Polyclonal Antibody for IHC (P), Western Blot
CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.
Especificaciones
| CD148 | |
| Polyclonal | |
| Unconjugated | |
| PTPRJ | |
| AI450271; BET; Byp; CD148; CD148 antigen; colon tumor susceptibility 1; density enhanced phosphatase-1; density-enhanced phosphatase 1; DEP1; DEP-1; HPTP beta-like tyrosine phosphatase; HPTP eta; HPTPeta; human density enhanced phosphatase-1; protein tyrosine phosphatase, receptor type J; protein tyrosine phosphatase, receptor type, J; protein tyrosine phosphatase, receptor type, J polypeptide; protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; Ptpb2; PTPbeta2; Ptprj; Receptor-type tyrosine-protein phosphatase eta; R-PTP-ETA; RPTPJ; R-PTP-J; Scc1; Scc-1; Susceptibility to colon cancer 1; susceptibility to colon cancer 1, mouse, homolog of | |
| Rabbit | |
| Antigen affinity chromatography, Protein A | |
| RUO | |
| 19271, 5795 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 | |
| Q12913, Q64455 | |
| PTPRJ | |
| Recombinant protein Density Enhanced Phosphatase 1. The antigen corresponds to amino acid range 567-842 of the target protein. | |
| 200 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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