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CD146 Mouse anti-Human, Brilliant Violet 786, Clone: P1H12, BD Optibuild™

Código de producto. 15818159
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Cantidad:
50 μg
Tamaño de la unidad:
cada uno
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15818159 50 μg cada uno
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Código de producto. 15818159 Proveedor BD Biosciences N.º de proveedor 743303

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Mouse Monoclonal Antibody

The P1H12 monoclonal antibody specifically binds to CD146. CD146 is a 118 kDa transmembrane glycoprotein also known as MCAM, MUC18, or Mel-CAM. CD146 is a member of the immunoglobulin superfamily strongly expressed by blood vessel endothelium and smooth muscle. CD146 is also expressed by angioblasts, mesenchymal stem cells, melanoma cells, intermediate trophoblasts and a subpopulation of activated T cells. The P1H12 monoclonal antibody has been reported to block endothelial cell adhesion that is observed very early in embryogenesis. It can be useful in the study of embryologic vasculogenesis. This antibody is suitable for immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation and ELISA.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter). BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm. BV786 offers a bright choice for the 6th detector off the violet laser.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CD146
Clasificación Monoclonal
Clon P1H12
Concentración 0.2mg/mL
Conjugado Brilliant Violet 786
Formulación Aqueous buffered solution containing ≤0.09% sodium azide.
Alias de gen MCAM, MELCAM, MUC18, Gicerin, Melanoma cell adhesion molecule
Especie del huésped Mouse
Inmunógeno Human Umbilical Vein Cells
Método de purificación Affinity Purified
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
Especies diana Human
Contenido y almacenamiento Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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