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Invitrogen™ CD138 Recombinant Rabbit Monoclonal Antibody (JM11-21)
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Código de producto. 16306014
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Cantidad:
100 μL
Packungsgröße:
100 microlitros
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16306014 100 μL 100 microlitros
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Artikelnummer. 16306014 Lieferant Invitrogen™ Lieferanten-Nr. MA532600

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Beschreibung

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
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Spezifikation

Antígeno CD138
Aplicaciones Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Clasificación Recombinant Monoclonal
Clon JM11-21
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
génica Sdc1
N.º de referencia del gen P18827, P18828, P26260
Alias de gen AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin
Símbolos de los genes Sdc1
Especie del huésped Rabbit
Inmunógeno Recombinant protein within Human Syndecan 1 aa 13-274.
Método de purificación Protein A
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 20969, 25216, 6382
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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