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CD138 Rat anti-Mouse, PE, Clone: 281-2, BD
Rat Monoclonal Antibody
189.00€ - 560.00€
Especificaciones
| Antígeno | CD138 |
|---|---|
| Clon | 281-2 |
| Concentración | 0.2mg/mL |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
15880739
|
BD Biosciences
561070 |
25 μg |
189.00€
cada uno |
Fecha estimada de envío: 06-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
15827348
|
BD Biosciences
553714 |
0.2 mg |
560.00€
cada uno |
Fecha estimada de envío: 15-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
The 281-2 monoclonal antibody specifically binds to the core protein of CD138 (Syndecan-1), a cell-surface, integral membrane heparan sulfate- and chondroitin sulfate-containing proteoglycan that binds to interstitial extracellular matrix molecules. Syndecan-1 is predominantly expressed on epithelial cells, where its expression correlates with normal epithelial organization. It is also expressed on B lymphocytes at specific stages during their differentiation: precursor B cells in the bone marrow and antibody-secreting cells, including plasma cells, but not mature peripheral B cells. It is thus implicated in mediating B cell-matrix interactions. CD138 expression is also regulated during embryonic development, and the molecule shows a tissue- specific structural polymorphism resulting from different post-translational modifications. The 281-2 antibody may be used to detect the differently glycosylated forms, because it reacts with the core protein. Furthermore, the mAb detects the Syndecan-1 ectodomain which is cleaved from cell surfaces by a metalloproteinase.
Especificaciones
| CD138 | |
| 0.2mg/mL | |
| Monoclonal | |
| Rat | |
| Mouse | |
| NAMRU mouse mammary gland epithelial cell line NMuMG | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| 281-2 | |
| Flow Cytometry | |
| PE | |
| RUO | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| IgG2a κ | |
| Affinity Purified | |
| SYND1; Syndecan-1; syn-1; Sdc1; Sstn; synstatin |
For Research Use Only.