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Invitrogen™ CD105 Monoclonal Antibody (3A9)

Descripción
MA5-17041 targets CD105 in indirect ELISA, FACS, ICC, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-17041 immunogen is purified recombinant fragment of human CD105 expressed in E. Coli. MA5-17041 detects CD105 which has a predicted molecular weight of approximately 71kDa.
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Especificaciones
Especificaciones
| Antígeno | CD105 |
| Aplicaciones | ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Clasificación | Monoclonal |
| Clon | 3A9 |
| Concentración | Conc. Not Determined |
| Conjugado | Unconjugated |
| Formulación | Ascites with 0.03% sodium azide |
| génica | ENG |
| N.º de referencia del gen | P17813 |
| Alias de gen | AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein |
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Título del producto
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