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PeproTech CCL3L1 Polyclonal Antibody, PeproTech®, Invitrogen™

Código de producto. 17875313
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Cantidad:
1 mg
100 μg
50 μg
Tamaño de la unidad:
1 miligramo
100 microgramos
50 microgramos
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17875313 50 μg 50 microgramos
17865403 100 μg 100 microgramos
17865483 1 mg 1 miligramo
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Código de producto. 17875313 Proveedor PeproTech N.º de proveedor 500P187G50UG

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Descripción

Goat Polyclonal Antibody

AA Sequence of recombinant protein: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human LD78beta (CCL3L1). Anti-Human LD78beta (CCL3L1)-specific antibody was purified by affinity chromatography employing an immobilized Human LD78beta (CCL3L1) matrix. Sandwich ELISA: To detect Human LD78beta (CCL3L1) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human LD78beta (CCL3L1) (500-P187GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human LD78beta (CCL3L1). Western Blot: To detect Human LD78beta (CCL3L1) by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human LD78beta (CCL3L1) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno CCL3L1
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica CCL3L1
N.º de referencia del gen P16619
Alias de gen 464.2; C-C motif chemokine 3-like 1; C-C motif chemokine ligand 3 like 1; CC-chemokine (CCL3); MIP1a; CCL3L1; CCL3L3; chemokine (C-C motif) ligand 3-like 1; chemokine ligand 3-like 1; D17S1718; G0/G1 switch regulatory protein 19-2; G0S19-2; LD78; LD78BETA; LD78-beta(1-70); LD78-beta(3-70); LD78-beta(5-70); macrophage inflamatory protein 1 alpha; MIP1AP; PAT 464.2; SCYA3L; SCYA3L1; small inducible cytokine A3-like 1; Small-inducible cytokine A3-like 1; Tonsillar lymphocyte LD78 beta protein
Símbolos de los genes CCL3L1
Especie del huésped Goat
Inmunógeno E.coli-derived Recombinant Human LD78beta (CCL3L1).
Método de purificación Antigen affinity chromatography
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 6349
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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