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Descripción
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predomitly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Specifikationer
Specifikationer
| Antígeno | Cathepsin K |
| Aplicaciones | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Clasificación | Polyclonal |
| Concentración | 0.37 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | CTSK |
| N.º de referencia del gen | O35186, P43235, P55097 |
| Alias de gen | Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, CTS02, CTSK, CTSO, CTSO1, CTSO2, PKND, PYCD |
| Símbolos de los genes | Ctsk |
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Produkttitel
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