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Invitrogen™ Cathelicidin Monoclonal Antibody (H7)
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Código de producto. 15334321
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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15334321 100 μL 100 microlitros
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Código de producto. 15334321 Proveedor Invitrogen™ N.º de proveedor MA518048

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Mouse Monoclonal Antibody

This antibody is specific for human Cathelicidin (aa 115-121, NQARGSF). The immunogen was prepared using partially purified human neutrophil membrane proteins (heparin Ultrogellectin affinity purification fractions in octyl glucoside). This target has a predicted molecular weight of 19 kDa.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Cathelicidin
Aplicaciones Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon H7
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.09% sodium azide
génica CAMP
N.º de referencia del gen P49913
Alias de gen 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Símbolos de los genes CAMP
Especie del huésped Mouse
Inmunógeno Partially purified human neutrophil membrane proteins (heparin Ultrogellectin affinity purification fractions in octyl glucoside).
Método de purificación Protein G
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 820
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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