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Invitrogen™ Caspase 3 Polyclonal Antibody
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Código de producto. 10252730
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Cantidad:
400 μL
Tamaño de la unidad:
100 microgramos
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Código de producto. Cantidad unitSize
10252730 400 μL 100 microgramos
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Product Code. 10252730 Supplier Invitrogen™ Supplier No. PA514504

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Description

Rabbit Polyclonal Antibody

Caspase 3 Polyclonal Antibody for Western Blot, IHC (P), Flow

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno Caspase 3
Aplicaciones Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 1.7 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.09% sodium azide; pH 7.4
génica CASP3
N.º de referencia del gen P42574
Alias de gen A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Símbolos de los genes CASP3
Especie del huésped Rabbit
Inmunógeno KLH conjugated synthetic peptide between 60-90 amino acids from the central region of human Caspase-3 (CASP3).
Método de purificación Ammonium sulfate precipitation, Size-exclusion - Dialysis
Cantidad 400 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 836
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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