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Invitrogen™ Caspase 3 Polyclonal Antibody
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Código de producto. 16386594
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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16386594 100 μL 100 microlitros
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Código de producto. 16386594 Proveedor Invitrogen™ N.º de proveedor PA577887

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Descripción

Rabbit Polyclonal Antibody

Positive Control: HeLa, HeLa (30 μM Cisplatin treatment for 24 hr), PC-12 (30uM cisplatin treatment for 24h), PC-12, Rat2, C8D30, NIH-3T3, Raw264.7, C2C12, Jurkat, Raji, NCI-H929, K562, THP-1, HL-60 Predicted Reactivity: Dog (89%), Cat (87%), Pig (88%), Rabbit (86%), Chimpanzee (99%), Bovine (84%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Caspase 3
Aplicaciones Dot Blot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 0.15 mg/mL
Conjugado Unconjugated
Formulación PBS with 20% glycerol, 1% BSA and 0.025% ProClin 300, pH 7
génica CASP3
N.º de referencia del gen P42574, P55213, P70677
Alias de gen A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Símbolos de los genes CASP3
Especie del huésped Rabbit
Inmunógeno Recombinant protein encompassing a sequence within the center region of human Caspase 3. The exact sequence is proprietary.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 12367, 25402, 836
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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