missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ C2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5107086
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
Sequence homology: Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%.
Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Especificaciones
| C2 | |
| Polyclonal | |
| Unconjugated | |
| C2 | |
| ARMD14; C2; C3/C5 convertase; classical-complement pathway C3/C5 convertase; CO2; Complement C2; Complement C2a fragment; Complement C2b fragment; complement component 2; complement component 2 (within H-2S); complement component C2; complement factor C2; DADB-122G4.1; I79_016440; MHC complement component C2 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 717 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1.0 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide; pH 7.4 | |
| P06681 | |
| C2 | |
| Synthetic peptide directed towards the middle region of human C2 (aa 398-448). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido