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Invitrogen™ C14orf129 Monoclonal Antibody (2F2)

Descripción
Peptide Sequence: METDCNPMEL SSMSGFEEGS ELNGFEGTDM KDMRLEAEAV VNDVLFAVNN MFVSKSLRCA DDVAYINVET KERNRYCLEL TEAGLKVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKRDGQS.
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
Especificaciones
Especificaciones
| Antígeno | C14orf129 |
| Aplicaciones | ELISA, Western Blot, Immunocytochemistry |
| Clasificación | Monoclonal |
| Clon | 2F2 |
| Concentración | 1.0 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with no preservative; pH 7.4 |
| génica | GSKIP |
| N.º de referencia del gen | Q9P0R6 |
| Alias de gen | 4933433P14Rik; C14orf129; GSK3B interacting protein; GSK3beta interaction protein; GSK3-beta interaction protein; GSK3B-interacting protein; GSKIP; HSPC210; MGC4945; RGD1308470 |
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Título del producto
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