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Invitrogen™ C14orf129 Monoclonal Antibody (2F2)
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA524550
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Descripción
Peptide Sequence: METDCNPMEL SSMSGFEEGS ELNGFEGTDM KDMRLEAEAV VNDVLFAVNN MFVSKSLRCA DDVAYINVET KERNRYCLEL TEAGLKVVGY AFDQVDDHLQ TPYHETVYSL LDTLSPAYRE AFGNALLQRL EALKRDGQS.
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
Especificaciones
| C14orf129 | |
| Monoclonal | |
| 1.0 mg/mL | |
| PBS with no preservative; pH 7.4 | |
| Q9P0R6 | |
| GSKIP | |
| C14orf129 (NP_057556.2, 1 a.a. ~ 139 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| ELISA, Western Blot, Immunocytochemistry | |
| 2F2 | |
| Unconjugated | |
| GSKIP | |
| 4933433P14Rik; C14orf129; GSK3B interacting protein; GSK3beta interaction protein; GSK3-beta interaction protein; GSK3B-interacting protein; GSKIP; HSPC210; MGC4945; RGD1308470 | |
| Mouse | |
| Protein A | |
| RUO | |
| 51527 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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