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Invitrogen™ BRUCE Polyclonal Antibody
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Product Code. 15920025
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Cantidad:
100 μL
Unit Size:
100 microlitros
Product Code. Cantidad unitSize
15920025 100 μL 100 microlitros
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Product Code. 15920025

Brand: Invitrogen™ PA567360

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GSTDNESCTNS ELNSPLVRRT LPVLLLYSIK ESDEKAGKIF SQMNNIMSKS LHDDGFTVPQ IIEMELDSQE QLLLQDPPVT YIQQFADAA Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.

Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno BRUCE
Aplicaciones Immunocytochemistry
Clasificación Polyclonal
Concentración 0.2 mg/mL
Conjugado Unconjugated
Formulación PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
génica BIRC6
N.º de referencia del gen Q9NR09
Alias de gen A430032G04Rik; A430040A19Rik; AA501170; APOLLON; baculoviral IAP repeat containing 6; baculoviral IAP repeat-containing 6; baculoviral IAP repeat-containing protein 6; baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6; BIR repeat-containing ubiquitin-conjugating enzyme; Birc6; BRUCE; D630005A10Rik; KIAA1289; mKIAA1289; RING-type E3 ubiquitin transferase BIRC6; Ubiquitin-conjugating BIR domain enzyme apollon; ubiquitin-conjugating BIR-domain enzyme apollon
Símbolos de los genes BIRC6
Especie del huésped Rabbit
Inmunógeno Recombinant Human BRUCE. Recombinant protein control fragment (Product #RP-108015).
Método de purificación Antigen Affinity Chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 57448
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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