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  6. BRCA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

BRCA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Código de producto. p-7209215 Tienda Proteintech Productos
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Cantidad:
150 μL
20 μL
Tamaño de la unidad:
150 microlitros
20 microlitros
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Código de producto. Cantidad unitSize
16839274 20 μL 20 microlitros
16829274 150 μL 150 microlitros
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Product Code. 16839274 Supplier Proteintech Supplier No. 197911AP20UL

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Description

Rabbit Polyclonal Antibody

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintece of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.

Specifications

Antígeno BRCA2
Aplicaciones Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 0.13 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
génica BRCA2
N.º de referencia del gen O35923, P51587, P97929
Alias de gen BRCA2, BRCC2, breast cancer 2, early onset, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1
Símbolos de los genes Brca2
Especie del huésped Rabbit
Inmunógeno Peptide
Método de purificación Antigen Affinity Chromatography
Cantidad 20 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 12190, 360254, 675
Especies diana Mouse, Human, Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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