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Invitrogen™ BAMBI Polyclonal Antibody

Descripción
Immunogen sequence: NKRLQDQRQQ MLSRLHYSFH GHHSKKGQVA KLDLECMVPV SGHENCCLTC DKMRQADLSN DKILSLVHWG MYSGHGKLEF V Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 98%.
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
Especificaciones
Especificaciones
| Antígeno | BAMBI |
| Aplicaciones | Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | BAMBI |
| N.º de referencia del gen | Q13145 |
| Alias de gen | 2610003H06Rik; BAMBI; BMP and activin membrane bound inhibitor; BMP and activin membrane-bound inhibitor; BMP and activin membrane-bound inhibitor homolog; BMP and activin membrane-bound inhibitor, homolog; kinase-deficient TGFbeta superfamily receptor subunit; NMA; Non-metastatic gene A protein; putative transmembrane protein NMA |
| Símbolos de los genes | BAMBI |
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Título del producto
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