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Descripción
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some maligt tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Especificaciones
Especificaciones
| Antígeno | ATG4A |
| Aplicaciones | Western Blot, Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.27 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | ATG4A |
| N.º de referencia del gen | Q8C9S8, Q8WYN0 |
| Alias de gen | APG4A, ATG4A, AUTL2, Autophagin 2, Cysteine protease ATG4A, hAPG4A |
| Símbolos de los genes | Atg4a |
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Título del producto
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