AROS Polyclonal Antibody, Invitrogen™

Descripción

Immunogen sequence: CRDHLRVNLK FLTRTRSTVA ESVSQQILRQ NRGRKACDRP VAKTKKKKAE GTVFTEEDFQ KFQQEYFGS Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 76%.

AROS, a nucleolar protein with an unknown function, interacts with extra ribosomal protein RPS19, playing a role in the signaling pathways that regulate rRNA transcription. The deduced amino acid sequence of AROS, derived from cDNA, defines an isoelectric point of 11.3. No known functional motifs were found in AROS except a short polylysine tract embedded in a putative nucleolar localization signal. At a basal level the protein is expressed ubiquitously with a significantly high level of expression in some tissues. Human AROS gene is mapped to chromosome 22q13.1.