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Invitrogen™ Aromatase Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA116532
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Descripción
This antibody is expected to react with equine (91%), bovine and rabbit (90%), porcine (83%), ovine, goat and canine (81%) based on sequence homology. Suggested positive control: antigen standard for CYP19A1 (transient overexpression lysate), human Fetal Temporal Lobe protein.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
Specifications
| Aromatase | |
| Polyclonal | |
| Unconjugated | |
| Cyp19a1 | |
| Ar; ArKO; ARO; ARO1; Arom; Aromatase; aromatase 1; aromatase cytochrome P450; aromatase cytochrome P450 19A1; CPV1; CYAR; Cyp19; Cyp19a; Cyp19a1; CYP19P1; CYPXIX; CYPXIXA1; Cytochrome P450 17-alpha; cytochrome P450 19 type I; Cytochrome P450 19A1; cytochrome P450 aromatase; cytochrome P-450 aromatase; cytochrome P-450 aromatase (alt.); cytochrome P450 family 19 subfamily a; cytochrome P450 family 19 subfamily A member 1; Cytochrome P450, 19, aromatase; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, family XIX (conversion of androgen to estrogen), aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; cytochrome P450, subfamily 19; cytochrome P450, subfamily XIX (aromatization of androgens); cytochrome P-450AROM; estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; Int5; Int-5; MGC104309; microsomal monooxygenase; P450AROM; P-450AROM; type III cytochrome p450 aromatase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100328545, 13075, 1588, 25147 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1.0 mg/mL | |
| PBS with 0.02% sodium azide | |
| P11511, P22443, P28649, Q29605 | |
| Cyp19a1 | |
| A synthetic peptide made to a C-terminal portion of the human Aromatase protein (between residues 400-502). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Rabbit, Monkey | |
| Antibody | |
| IgG |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Aromatase Polyclonal Antibody
Signal Word
- Atención
Hazard Category
- Toxicidad aguda Categoría 4
Hazard Statement
- H302-Nocivo en caso de ingestión.
Precautionary Statement
- P260-No respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.
- P264-Lavarse concienzudamente tras la manipulación.
- P301+P330+P331-EN CASO DE INGESTIÓN: Enjuagarse la boca. NO provocar el vómito.
- P501b-Eliminar el contenido/el recipiente en conforme a la reglamentación local/regional/nacional/internacional.
Supplemental information
- MIXTURE LIST-Contém: Citric acid
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