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Vβ 8.3 T-Cell Receptor Hamster anti-Mouse, PE, Clone: 1B3.3, BD
Hamster Monoclonal Antibody
Marca: BD Biosciences 553664
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Descripción
The 1B3.3 antibody reacts with the Vβ 8.3 T-cell Receptor (TCR), but not the Vβ 8.1 nor Vβ 8.2 TCR, of mice having the b haplotype (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C58, DBA/1, DBA/2) of the Tcrb gene complex. The Tcrb-V8 subfamily gene loci are deleted in mice having the a (e.g., C57BR, C57L, SJL, SWR) or c (e.g., RIII) haplotype. Vβ 8.3 is one of the restricted TCR β chains expressed by NK-T cells. Staphylococcal enterotoxin B, in association with antigen-presenting cells expressing I-A and/or I-E, stimulates lymphocytes bearing Vβ 8 TCR and selectively eliminates those T cells in vivo. Vβ 8.3 TCR-bearing T-cell clones can be activated by 1B3.3 mAb. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes.
Host Species: Hamster
Clone: 1B3.3
Isotype: IgG3, λ1
Species Reactivity: Mouse
Immunogen: Vβ 8.3 TCR-expressing mouse Th1 clone 3.L2
Flow Cytometry
Especificaciones
| Vβ 8.3 T-Cell Receptor | |
| Monoclonal | |
| 0.2mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Vβ 8.3 TCR-expressing mouse Th1 clone 3.L2 | |
| 0.1 mg | |
| Immunology | |
| Mouse | |
| IgG3 |
| Flow Cytometry | |
| 1B3.3 | |
| PE | |
| Hamster | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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