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TPP1, Mouse, Clone: 3B1, Abnova™
Mouse monoclonal antibody raised against a partial recombinant TPP1.
Marca: Abnova H00001200-M01.100ug
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Descripción
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
Sequence: GLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFEspecificaciones
| TPP1 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC014863 | |
| TPP1 | |
| TPP1 (AAH14863, 195 a.a. ∼ 304 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| ELISA, Immunohistochemistry (PFA fixed), Western Blot | |
| 3B1 | |
| Mouse monoclonal antibody raised against a partial recombinant TPP1. | |
| TPP1 | |
| CLN2/GIG1/LPIC/MGC21297 | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 1200 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Liquid |
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