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transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A), Mouse, Clone: 1F3, Abnova™
Mouse monoclonal antibody raised against a partial recombinant TCEB3.
Marca: Abnova H00006924-M02.100ug
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Descripción
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq
Sequence: NAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYEspecificaciones
| transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_003198 | |
| TCEB3 | |
| TCEB3 (NP_003189, 81 a.a. ∼ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Transcription Regulation | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Immunofluorescence, Western Blot | |
| 1F3 | |
| Mouse monoclonal antibody raised against a partial recombinant TCEB3. | |
| TCEB3 | |
| FLJ38760/FLJ42849/SIII/TCEB3A | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Yes | |
| 6924 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2a κ |
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